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Image Search Results


MS/MS spectra of IAM derivatives including ( A ) Cys, ( B ) Hcy, ( C ) GSH, ( D ) NAC, ( E ) Cys-Gly, ( F ) Glu-Cys, ( G ) CA, and ( H ) d4-Hcy with 20 V collision energy.

Journal: Metabolites

Article Title: Iodoacetamine-Alkyne Derivatization-Based Liquid Chromatography–Mass Spectrometry Method for Quantification of Thiol Metabolites in Serum Samples of Hepatocellular Carcinoma Patients

doi: 10.3390/metabo16050345

Figure Lengend Snippet: MS/MS spectra of IAM derivatives including ( A ) Cys, ( B ) Hcy, ( C ) GSH, ( D ) NAC, ( E ) Cys-Gly, ( F ) Glu-Cys, ( G ) CA, and ( H ) d4-Hcy with 20 V collision energy.

Article Snippet: Cys-Gly, deuterated HCy (d4-Hcy), and Glu-Cys were obtained from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China).

Techniques: Tandem Mass Spectroscopy

Concentration distributions of Cys, Hcy, GSH, and Cys-Gly in serum samples from HCC and healthy controls (CTLs) within both the discovery and validation cohorts. Statistical significance was assessed using the Mann–Whitney U test: * p < 0.05, ** p < 0.01.

Journal: Metabolites

Article Title: Iodoacetamine-Alkyne Derivatization-Based Liquid Chromatography–Mass Spectrometry Method for Quantification of Thiol Metabolites in Serum Samples of Hepatocellular Carcinoma Patients

doi: 10.3390/metabo16050345

Figure Lengend Snippet: Concentration distributions of Cys, Hcy, GSH, and Cys-Gly in serum samples from HCC and healthy controls (CTLs) within both the discovery and validation cohorts. Statistical significance was assessed using the Mann–Whitney U test: * p < 0.05, ** p < 0.01.

Article Snippet: Cys-Gly, deuterated HCy (d4-Hcy), and Glu-Cys were obtained from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China).

Techniques: Concentration Assay, Biomarker Discovery, MANN-WHITNEY

( A ) ROC curves of Cys, Hcy, GSH, Cys-Gly, and the combined Cys and Cys-Gly model in the discovery set, ( B ) ROC curve of the combined Cysand Cys-Gly diagnostic model in the validation set.

Journal: Metabolites

Article Title: Iodoacetamine-Alkyne Derivatization-Based Liquid Chromatography–Mass Spectrometry Method for Quantification of Thiol Metabolites in Serum Samples of Hepatocellular Carcinoma Patients

doi: 10.3390/metabo16050345

Figure Lengend Snippet: ( A ) ROC curves of Cys, Hcy, GSH, Cys-Gly, and the combined Cys and Cys-Gly model in the discovery set, ( B ) ROC curve of the combined Cysand Cys-Gly diagnostic model in the validation set.

Article Snippet: Cys-Gly, deuterated HCy (d4-Hcy), and Glu-Cys were obtained from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China).

Techniques: Diagnostic Assay, Biomarker Discovery